Cefiderocol is a siderophore cephalosporin with a unique mechanism for penetrating efficiently into Gram-negative pathogens.
Cefiderocol binds to free iron and is actively transported into bacterial cells through the outer membrane.
This Trojan horse strategy allows cefiderocol to enter the space in-between the bacterial cell walls and disrupt cell wall synthesis.
In addition, cefiderocol is stable against nearly all beta-lactamases, including both the serine and metallo-carbapenemases.
Cefiderocol 30 ?g disk (CE marked) is available by Liofilchem in three packaging formats:
1 canister, 250 disks
1 cartridge, 50 disks
5 cartridges, 250 disks
-20°C storage temperature
12 months shelf life